阎浩，医学博士，研究员，博士研究生导师，医技科副主任，主持影像中心工作。

主要经历

2004年本科毕业于天津医科大学临床医学专业，2009年毕业于北京大学，获医学博士学位。2015年曾受邀前往美国约翰斯·霍普金斯大学Lieber脑发育研究所开展合作研究。

科研工作

科研项目：主持国家自然科学基金青年和面上项目共计5项、北京市自然科学基金面上项目1项、首都卫生发展科研专项自主创新项目1项、教育部高等学校博士学科点专项科研基金1项、北京大学临床医学+X青年专项1项并获延伸资助，以及其他多项院校级项目；作为参加单位负责人和课题骨干参与科技部“重大慢性非传染性疾病防控研究”重点专项和北京市“脑科学研”技专项计划、国家自然科学基金重点项目、基金委和科技部国际合作项目、国家“863”、“973”计划项目等科研项目。

研究方向：生物精神病学，聚焦精神障碍精准诊疗研究，针对抑郁障碍、精神分裂症及青少年自伤，基于脑影像表型，发展风险分层、疗效预测和影像引导的精准神经调控技术。目前主要研究兴趣包括：

v  影像学指标与药物及非药物治疗效应的关联。开展抗精神病药疗效和不良反应的影像遗传研究，以及个体化神经调控治疗抑郁发作的疗效和影像预测特征研究。

v  青少年常见精神障碍合并自伤行为的认知和神经机制。开展神经调控与心理治疗干预自伤行为疗效和神经机制研究；与合作者共同探索自伤行为决策行为的认知和神经机制。

v  遗传和环境效应对疾病相关脑环路的风险和保护作用。采用多模态融合等方法关注疾病遗传和环境因素对精神分裂症、抑郁症等常见精神疾病相关大脑神经环路及行为的影响。

发表论文：上述研究工作已发表论著100余篇，其中第一/通讯作者35篇，发表在American Journal of Psychiatry, Biological Psychiatry, Translational Psychiatry, Schizophrenia Bulletin, Cerebral Cortex, Neuroimag等SCI收录杂志和国内核心期刊。参编大型工具书《沈渔邨精神病学（第6版）》、《牛津精神病学（第七版）》等。

社会任职服务

目前担任中国女医师协会精神卫生专委会委员、北京慢性病防治与健康教育研究会精神卫生学专委会委员、中国残疾人康复协会脑功能精准调控专委会常务委员、中国心理卫生杂志社编委；自然基金函审专家、教育部学位论文盲审专家、临床研究国家级质量评价和促进中心专家（精神健康和疾病领域）、Frontiers in Human Neuroscience副编辑；Biological Psychiatry、eBioMedicine, BMJ Mental Health, Psychological Medcinie、Neuroscience Bulletin、中国心理卫生等学术期刊审稿人。

近五年代表性论著

1.        Li M, Wu Z, Lu X, Zalesky A, Cheng X, Zhang Y, Cash RFH, Jin F, Jia S, Xiao Y, Zhong G, Zhang X, Yue W, Yang Z*, Jiang T*, Yan H*. Individualized Connectivity-Guided Versus Conventional Targeting of Accelerated Theta-Burst Stimulation in Depression: A Randomized, Double-Blind, Parallel-Design Trial. Am J Psychiatry. 2026 Aug 12:appiajp20251084. doi: 10.1176/appi.ajp.20251084. Epub ahead of print. PMID: 42581396.

2.        Xiao Y, Li M, Liao J, Yan J, Li Z, Guo H, Pu C, Yu X, Zhang D, Yue W, Yan H*. CINP: a causality-informed framework for generalizable and replicable neuroimaging prediction of antipsychotic response in schizophrenia. Biol Psychiatry. 2026 Mar 13:S0006-3223(26)01103-0. doi: 10.1016/j.biopsych.2026.03.988. Epub ahead of print. PMID: 41833746.

3.        Li M#, Xiao Y#, Ge Y, Yan H, Li X, Yue W, Yan H*. Functional heterogeneity in non-suicidal self-injury across psychiatric disorders: neural and psychosocial correlates. Transl Psychiatry. 2026 Jan 6;16(1):60. doi: 10.1038/s41398-025-03802-9. PMID: 41495020; PMCID: PMC12873407.

4.        Zhao G#, Sun Y#, Zhang Y#, Lu T, Lu Z, Kang Z, Schneider-Thoma J, Xie W, Yang Y, Guo J, Zhu Y, Yuan R, Sun J, Feng X, Liao Y, Chen D, Li L, Li T, Yang F, Wang C, Zhang D*, Yan H*, Leucht S*, Yue W*; Schizophrenia in Non-Occidental Participants (SINO) Investigators. Efficacy and Tolerability of Seven Antipsychotic Drugs in Acutely Ill Patients With Schizophrenia: A Randomized, Multicenter, Assessor-Blinded Trial. Am J Psychiatry. 2025 Oct 29:appiajp20250111. doi: 10.1176/appi.ajp.20250111. Epub ahead of print. PMID: 41152254.

5.        Xiao Y#, Li M#, Zhang X, Zhang Y, Ge Y, Lu Z, Ma M, Song Y, Tan HY, Zhang D, Yue W, Yan H*. Deviations From Normative Functioning Underlying Emotional Episodic Memory Revealed Cross-Scale Neurodiverse Alterations Linked to Affective Symptoms in Distinct Psychiatric Disorders. Biol Psychiatry Glob Open Sci. 2025 May 14;5(5):100534. doi: 10.1016/j.bpsgos.2025.100534. PMID: 40636099; PMCID: PMC12240089.

6.        Lu YL#, Ge Y#, Li M, Liang S, Zhang X, Sui Y, Yang L, Li X, Zhang Y, Yue W, Zhang H*, Yan H*. Cognitive Phenotype Shifts in Risk-Taking: Interplay of Non-Suicidal Self-Injury Behaviors and Intensified Depression. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Jun 11:S2451-9022(24)00157-5.

7.        Ge Y, Xiao Y, Li M, Yang L, Song P, Li X, Yan H*. Maladaptive cognitive regulation moderates the mediating role of emotion dysregulation on the association between psychosocial factors and non-suicidal self-injury in depression. Front Psychiatry. 2023 Nov 30;14:1279108.

8.        Wang X#, Mei D#, Lu Z, Zhang Y, Sun Y, Lu T, Yan H*, Yue W*. Genome-wide association study identified six loci associated with adverse drug reactions to aripiprazole in schizophrenia patients. Schizophrenia (Heidelb). 2023 Jul 25;9(1):44.

9.        Zhang Y#, Li M#, Zhang X#, Zhang D, Tan HY, Yue W*, Yan H*. Unsuppressed Striatal Activity and Genetic Risk for Schizophrenia Associated With Individual Cognitive Performance Under Social Competition. Schizophr Bull. 2022 May 7;48(3):599-608.

10.     Zhang Y, Liao J, Li Q, Zhang X, Liu L, Yan J, Zhang D, Yan H*, Yue W*. Altered Resting-State Brain Activity in Schizophrenia and Obsessive-Compulsive Disorder Compared With Non-psychiatric Controls: Commonalities and Distinctions Across Disorders. Front Psychiatry. 2021 May 21;12:681701.

11.     Cheng W#, Luo N#, Zhang Y, Zhang X, Tan H, Zhang D, Sui J* Yue W*, Yan H*. DNA Methylation and Resting Brain Function Mediate the Association between Childhood Urbanicity and Better Speed of Processing. Cereb Cortex. 2021 May 14;31(10):4709–18.

12.     Li Q#, Yan J#, Liao J, Zhang X, Liu L, Fu X, Tan HY, Zhang D*, Yan H*. Distinct Effects of Social Stress on Working Memory in Obsessive-Compulsive Disorder. Neurosci Bull. 2021 Jan;37(1):81-93.

13.     Zhang X#, Yan H#, Yu H, Zhao X, Shah S, Dong Z, Yang G, Zhang X, Muse T, Li J, Jiang S, Liao J, Zhang Y, Chen Q, Weinberger DR, Yue W, Zhang D*, Tan HY*. Childhood urbanicity interacts with polygenic risk for depression to affect stress-related medial prefrontal function. Transl Psychiatry. 2021 Oct 12;11(1):522.